- heart problems, including heart attacks
- respiratory effects, including respiratory failure
- nervous system problems, including strokes
- digestive problems
- contracting HIV and other diseases (by Injecting cocaine using shared needles)
- serious skin infections
- severe allergic reactions
Like other forms of drug addiction, cocaine dependence results from the effect the drug has on the brain that results in feelings of intense pleasure. Cocaine works as a stimulant drug by increasing the levels of the brain chemicals, especially dopamine. Under ordinary circumstances, lower amounts of dopamine are produced in response to the pleasurable activities we all experience as a natural part of our everyday lives.
Cocaine produces its euphoric effect in two ways:
- Artificially increasing the release of dopamine
- Preventing the normal re-absorption of dopamine back into the brain’s nerve cells
In all cases of habitual cocaine abuse and addiction the body builds a tolerance to the increased levels of dopamine, and progressively larger amounts of cocaine are required by the user to achieve the sensation of being high.
Commonly, cocaine abusers experience long-term changes in the brain’s reward system and in other brain systems. This can result in unusual or unpredictable behavior toward those around them. Many cocaine abusers become frustrated when their increased tolerance results in a failure to achieve the high they did from their initial exposures. They often then increase their dosage in an attempt to intensify and prolong the effect; this heightens the risk of adverse physiological or psychological effects, as well as the risk of a potentially deadly overdose. Also, using cocaine with alcohol increases the likelihood that the user will become a victim of a drug-related death.
Typical Signs of Sleep Deprivation and Insomnia.
Irritability. This isn't your typical "I just don't want to be bothered right now". This is a growing anger and near hatred of everything and everyone around you. This symptom of sleep deprivation will cause you to snap at the littlest things and boil over in anger at the most trivial of mistakes. You'll quickly know whether or not this level of "intolerance" is normal for you.
Tiredness. An unwavering, incessant feeling of "I just want to lay down and do nothing". In fact, doing nothing and thinking nothing sounds like the PERFECT idea and you want to start right now -- even if you're at work in the middle of a board meeting. Any task, be it big or small, is just too much work for you to handle and you want nothing more than to just sit or lay somewhere peacefully. You are quite literally sapped of energy.
Socially Inept. This isn't being "shy", this interacting with a wall who has recently been reincarnated into a human being. The things you say to people are incomprehensible and things said to you might as well be in a whole different language. Unlike the irritability symptoms of sleep deprivation, you're fine with everyone around you and you don't even mind talking to people -- you just can't understand what they are saying nor can you communicate effectively with them.
Note: If you're not real big talker or a "social butterfly" as its called, then this is one of those symptoms of sleep deprivation that you're bound to miss.
If You Have Any Of These Symptoms, Then Consider Using This Natural Insomnia Cure Instead of OTC Sleep Aids. More Often Than Not, Regular Use of Sleeping Pills Worsen Insomnia Problems.
Stress Cracker. Just as it says, this sign of sleep deprivation causes you to crack, fold, and just topple-over from any amount of stress or pressure. You feel like the whole world is on your shoulders and you can't solve any problem you are faced with. You feel, in a word, helpless.
Memory Loss. You aren't brain damaged or anything, but the lack of sleep and severe sleep deprivation has definitely impaired your cognition. Seconds, minutes, or hours ago, it doesn't matter -- you just can't recollect anything specifically in your mind. Its more of a "hazy" memory rather than an all together non-existent one.
Bad Concentration. One of the many signs of sleep deprivation that can seriously interfere in the work place. You just can't seem to focus on anything you're doing, no matter how inconsequential it may seem. Not only do you have poor focus and mental concentration, but your reaction time is slowed significantly as well. This is one of the more serious effects of insomnia as it literally has an affect on EVERYTHING you do.
Strange Appetite Changes. This symptom of sleep deprivation will cause you to either be super hungry all the time or it'll make you not want to eat anything at all, ever. Whatever the case may be, it's definitely not a normal thing and you may wind up losing weight or even gaining weight depending on how long this period of sleep deprivation lasts.
So, are these symptoms of sleep deprivation affecting you? If they are, then it's time to do something about it and treat your sleeplessness before it gets worse. These signs of sleep deprivation might not like seem like a big deal when they first appear, but don't be fooled, they can and WILL interfere with how you live your life.
Lexapro withdrawal symptoms can, and will, appear if you stop taking the medication abruptly, even if you have only been taking it for a few weeks. Most doctors recommend and with prescribe a weaning or tapering dosage to decrease the likelihood of increased side effects. The Lexapro withdrawal symptoms can be quite unpleasant and harmful, especially if you have been taking a larger daily dose, and it is important to fully discuss the best course of action with your physician. Make sure that your family and/or friends are aware of the Lexapro withdrawal symptoms as well, so that they can keep an eye on you if you happen to be suffering them without your knowledge.
San Francisco, Calif.: Does the release of Tamiflu from U.S. stockpiles have any affect for the average citizen here? Is it now easily available?
Richard Wenzel: This is an effective anti-influenza drug, especially in preventing infection among exposed, but not ill people. It also has a modest effect in treatment. The drug is available.
Pork: Does swine flu have anything to do with eating tainted pork products?
Richard Wenzel: No. There is no risk of swine flu from eating appropriately cooked pork.
Anonymous: Thanks for taking the question. My family and I recently visited Cancun for spring break. My husband had felt achy, chilled and fatigued after returning home however had no sig cough. He has since improved however remains tired. Everyone else is fine. Any cause for concern?
Richard Wenzel: This is a difficult question. Approximately 20% of people have general fatigue after some infections like mononucleosis of cytomegalovirus and sometimes after influenza. It would be best to have a checkup with your physician.
Washington, D.C.: I heard that the Swine Flu is suppose to hit the Washington Area hard. Is this true and what can we do to protect ourselves?
Richard Wenzel: No one knows what cities will be hit, or how hard the virus will be. Because Washington, DC is an international city the chances of bringing infections from other countries and other cities is great. At this point, you should be alert to the degree of infections in your own city, report to a physician with respiratory infections and maintain careful hand washing. Despite the custom of handshaking, it is reasonable to avoid that custom for the time being.
Baltimore, Md.: I've read that this flu has disproportionately hit healthy young adults instead of children and elderly people. Any thoughts on why?
And do you think we will be raised to a WHO Phase 4 or 5 at this point?
Richard Wenzel: It is likely that people over age 60 have some cross reacting antibody from prior infection with a related virus in years past. This remains to be proved. Thus, young adults are disproportionately infected.
I am surprised that WHO did not already call this a level 4.
Signs of motor system dysfunction include the following:
- Difficulty starting movement
- Increased muscle tone, stiffness
- Muscle spasm
Other symptoms of RSD/CPRS include the following:
- Dermatitis, eczema (inflammation of the skin)
- Excessive sweating
- Migraine headache
Patients with any chronic illness, including CRPS, often suffer from depression and anxiety. Skin, muscle, and bone atrophy (wasting) are possible complications of this syndrome. Atrophy may occur because of reduced function of the affected limb.
Publication Review By: Eric M. Schreier, D.O., F.A.A.P.M.R.
Published: 30 Dec 1999
Last Modified: 02 Oct 2015
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The signs or symptoms of leukemia may vary depending on whether you have an acute or chronic type of leukemia.
Acute leukemia may cause signs and symptoms that are similar to the flu. They come on suddenly within days or weeks.
Lithium (150mg, taken once off Sodium Valproate, 6 months 2014)
Seroquel (750mg, 5 years, 2010 - 2014 )
Ritalin (50 mg per day in the past 6 months)
Lexapro is my last medication I am getting off now (under GP and psychiatrists supervisor / guidance). All other medications were weaned off of over a long period of time and in small increments.
I started going off Lexapro a two weeks ago (20 mg down to 10 mg), the first week I thought I was just getting my girlfriends flu.
Then I went from 10 mg to nothing.
This has been HELL!
Cold sores, mouth ulcers, lethargy, headaches, really bad insomnia, grumpy and unsociable.
I believe it must really weaken your immune system in order for this to happen.
The first week was great. I could think clearer. Tasks and university work began to become easier to do due to being able to think more in depth and sequentially.
I may have to redo my units but if I am able to think as clear as the first week I am willing to make that sacrifice.
Does anyone who has gone cold turkey after long periods on Lexapro as to how long the withdrawals symptoms last?
i too am weened off lexapro.. this is my 5th day off of my 10mg of 8 months not long i know.
but i don't want to be on these any more as me and my partner are trying to conceive i think this med is blocking it and keeping is from conceiving so if we get what we want at the end its the only thing giving me hope from these horrendous side effects.
I really hope i can push from it but all people blog about is how bad the side effects are and the beginning stage. what about after the withdrawals.. is there hope?
my symptoms are feeling faint light headed migraine sweats shivers and shaking cant concentrate and patchy skin if this is it then fine i can get over this.. but how long will it last? also i am extremely tired won't stop sleeping and signed off from work due to nearly collapsing..:(.
Hey I have only been on for 9 months at 10 mg and I dosed myself down to 5mg for the past 3 days. I am experiencing pain in my neck but nothing else anyone has been talking about. Did you have any physical pain?
Yes, these viruses change and adapt all the time. That's they're survival mechanism. They're constantly mutating, evolving, taking on new names and jumping from one animal to the next.
3) What about the bird flu that showed up in various parts of the world in 2006 and 2007? Was it the same as Asian flue or was it a slightly different strain of the virus? Does the virus keep changing?
2) @Steamland, as far as we know there are two reasons for this. One is just probability. Asia contains a huge portion of the world's population and is a massive part of the geographic world. People sometimes refer to Asia like it's a single country but about a third of the world is classified as Asia. Add in more than half the world's population and it makes sense than many of the worlds diseases would originate there. Also to blame is the developing nature of many regions within Asia. Not only do billions of people live relatively close together, some live close together in poor hygienic conditions with little access to proper sanitation and clean water. Compound this with the fact that a portion of these people live in close contact with farm animals. Farm animals, like ducks, chickens and pigs are usually the original hosts from which many new diseases mutate and make the jump to humans. Not only that but often these farm animals live in close proximity with each other which can promote mutation conditions in certain viruses and bacteria.
1) Why do all of these horrible pandemic diseases seem to come from Asia? Why don't they originate in places like America?
Flu shot reduces risk of rare Guillain-Barré Syndrome in most cases, study finds
Fear of developing Guillain-Barré Syndrome is often cited by health-care workers as a reason not to get a flu shot.
It's flu season. File photo
Fear of developing Guillain-Barré Syndrome is often cited by health-care workers as a reason not to get a flu shot.
But new research suggests that in most cases the flu vaccine actually reduces the risk of the rare disorder by cutting the risk of influenza.
Two Ottawa researchers — Kumanan Wilson, physician and senior scientist at The Ottawa Hospital and professor of medicine at the University of Ottawa, and Steven Hawken, a scientist at The Ottawa Hospital — were involved in the study published Wednesday in the U.S. Centre for Disease Control’s journal Emerging Infectious Diseases that assessed the effect of seasonal influenza vaccine on the risk of acquiring Guillain-Barré Syndrome (or GBS).
Guillain-Barré is a rare, but serious, autoimmune disorder that causes muscle weakness and sometimes paralysis. Most patients require hospitalization and about one-quarter require intensive care. Four per cent of patients will die within one year of developing the condition.
About 20 people out of every million will develop GBS. In most cases, GBS is preceded by a respiratory or gastrointestinal infection. Studies have shown it is associated with influenza.