Malignant mesothelioma generally develops in people over the age of sixty five and usually occurs in the chest cavity, arising in the pleura in sixty five to seventy percent of all cases. The other predominant location for mesothelioma cancer cases is the peritoneal lining of the organs in the abdominal cavity. It may also affect the pericardial lining of the heart, in rare cases.

  • Shortness of breath
  • Chest pain
  • Tightness in the chest
  • Persistent cough
  • Weight Loss
  • Fatigue

Pleural effusion is also a common development with mesothelioma. This condition is caused by accumulation of excess fluid in the space between the lungs and the chest wall or diaphragm. It can be the cause of chest pain and reduced breathing capacity.

Peritoneal mesothelioma is characterized by abdominal swelling and pain. This symptom can also be the result of fluid accumulation – in this case, within the abdominal cavity. Thickening of the peritoneal tissue can lead to additional symptoms:

  • Swelling
  • Weight loss
  • Nausea
  • Obstructed bowels
  • Anemia
  • Fever and/or night sweats

If you or someone you love is experiencing any symptoms of asbestos exposure, you should visit your doctor right away.

According to many experts, the symptoms of CRPS (sometimes called RSD) often progress in three stages—acute, dystrophic, and atrophic. The primary symptoms of CRPS is continuous, severe pain that gets worse over time, rather than better, and is not in proportion to the injury—if trauma has occurred. Usually CRPS affects one extremity (e.g., arm, leg, hand, foot).

The acute stage occurs during the first 1–3 months and may include

  • burning pain
  • swelling
  • increased sensitivity to touch
  • increased hair and nail growth in the affected region
  • joint pain
  • color and temperature changes

The dystrophic stage may involve constant pain and swelling. The affected limb may feel cool to the touch and appear bluish in color. Muscle stiffness, wasting of the muscles (atrophy) and early bone loss (osteoporosis) also may occur. This stage usually develops 3–6 months after onset of the disorder.

During the atrophic stage, the skin becomes cool and shiny, increased muscle stiffness and weakness occur, and symptoms may spread to another limb. At this stage, changes to the skin and bone usually are permanent.

Characteristic signs and symptoms of sympathetic nervous system involvement include the following:

  • Burning pain
  • Extreme sensitivity to touch
  • Skin color changes (red or bluish)
  • Skin temperature changes (hot or cold)

Pain caused by RSD/CRPS usually in not proportionate to the degree of injury. It can be triggered by disuse of the affected limb or by stress and can be spontaneous or constant.

Symptoms associated with an immune reaction include:

  • Joint pain
  • Redness
  • Swelling (edema)
  • Frequent infections

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Differences between flu and pregnancy symptoms

For a woman who has unexpectedly become pregnant, and possibly for the first time in her life, the most initial symptoms might seem just like another bout of the flu (also known as influenza).
The flu is an infectious disease, viral in origin. It is generally self-limiting and will settle down within a week or so. The flu affects all the systems of the body, whereas pregnancy will have more of gastrointestinal and genitor-urinary affections. The flu starts once a person comes in contact with another person who is suffering from it and it is extremely contagious. The flu is commonly seen in children who have low immunity.
Morning sickness (high degree of nausea and vomiting) is the most important symptom of pregnancy. Morning sickness is so called because the nausea is usually most severe in the mornings. It may subside in some patients after the first three months or it may continue up until the last month. It occurs due to a drop in blood sugar levels and an increase in circulating hormones. Nausea generally increases in the mornings, as there is a state of fasting the entire night leading to a dip in the blood glucose levels.
Symptoms of the flu are marked by a sudden onset of cold, cough, fever of mild degree and tremendous weakness due to joint pains and muscle pains. With the flu, patients will complain of severe headache and fever, whereas in pregnancy females will have more of a feeling of giddiness and dizziness. The spells occur especially while suddenly getting up from a sleeping position or during or after long hours of working. If the caloric needs are not met during pregnancy, it will lead to spells of such weakness and is seen commonly in females with poor food intake.
Flu patients have a reduced appetite due to altered taste sensations and hence face weight loss, but in pregnancy there is a sudden increase in the appetite and weight. It is due to the high energy needed in order to supply adequate nutrition to the growing baby. Flu symptoms will be short term and self-resolving, whereas pregnancy symptoms will be long-term and continue easily for the term of three months at a stretch. In the case of the flu affecting the gastro-intestinal tract, symptoms like diarrhea, cramps and pain in the lower abdomen, a fever and severe nausea and vomiting can be seen. Also, there will be signs of dehydration and fatigue. It should not be confused with morning sickness of pregnancy, as in pregnancy nausea will be present throughout the first three to four months but is intense usually only in the morning, subsiding for the remainder of the day and often is not relieved by medications. Typically, pregnant females have high sensitivity to odors of any kind and that will bring on the wave of nausea. Along with these symptoms, there is presence of tenderness of breasts, bloating of the abdomen, irresistible cravings for various foods, repeated heartburn and hyperacidity, etc.
Flu symptoms will be seen in any individual, be it male or female, of any age, whereas pregnancy occurs only in females of between the ages of 14 to 50 years. The flu can be controlled by asking the patient to ingest more fluids, rest and take anti-viral medications if needed. Also, the spread of the virus can be curbed by wearing masks, which will reduce air transfer. A pregnancy can be confirmed by doing a simple home urine pregnancy test or an ultrasound.

Summary: The flu is an infectious disease of viral origin causing symptoms like cold, cough, fever, etc. It will only affect after you contract the infection from other individuals, and hence should not be confused with pregnancy symptoms which will begin once conception starts.

rachita. "Difference between flu and pregnancy symptoms." October 5, 2017.

Written by: rachita. and updated on October 5, 2017

Influenza viruses continued to circulate in the Region with 28% of the individuals sampled from primary healthcare settings testing positive, while all countries reported low or medium intensity of activity of respiratory infections.

Both influenza virus types A and B were co-circulating with the majority being type A viruses.

  • Influenza has been circulating widely in the Region since week 52/2017, based on positivity rates among sentinel specimens, which is longer than in recent seasons and may contribute to the severity of this season.

For the Region overall, the majority of influenza viruses detected were type B, representing a high level of circulation of influenza B viruses compared to recent seasons. B/Yamagata lineage viruses have greatly outnumbered those of the B/Victoria lineage. Click here for more information

Different patterns of dominant type and A subtypes were observed between the countries of the Region. Influenza A viruses are now dominant in several eastern European countries.

Of the type A virus detections from sentinel sources, the majority of which were subtyped, A(H1N1)pdm09 viruses have outnumbered A(H3N2) viruses. In non-sentinel sources, more A(H3N2) viruses than A(H1N1)pdm09 viruses were reported. Click here for more information

While low in number, 55% of characterized A(H3N2) viruses belong to clade 3C.2a and 41% of B/Victoria lineage viruses belong to a subclade of clade 1A viruses that are antigenically distinct from the current trivalent vaccine component. Click here for more information

The majority of severe cases reported this season are due to influenza type B and have mostly occurred in persons above the age of 15 years. Click here for more information

Mortality from all causes based on pooled data from 1 9 EU countries and regions that reported to EuroMOMO remained elevated in some countries. Click here for more information

Interim results from 5 European studies indicate 25 to 52% vaccine effectiveness against any influenza. Click here for more information

Influenza or flu is an infectious disease that affects birds and mammals. It is caused by the different strains of the influenza virus. It causes infection of the respiratory tract and may lead to a wide range of symptoms that have been enumerated below. The transmission of this virus, usually takes place through air from mammal to mammal. For example, when a person infected with the influenza virus coughs, he releases some of the viruses into the air. The same air may be inhaled by another person, leading to an infection.
Many strains of the influenza virus are highly pathogenic in nature and have caused 3 pandemics in the last century. Apart from them, seasonal epidemics of influenza are also known to occur throughout the world.
The most recent influenza threat has been in the form of the H5N1 virus that affects birds. Still in its emerging stage, this virus is yet to adapt itself to humans. However, it poses the greatest pandemic threat in today's world.

If you are looking for reliable protection against flu, check Viral-Protec which boost resistance to flu and other viruses.

Influenza can cause a variety of symptoms. Once a person has been infected with the flu virus, the symptoms start appearing within 1 to 4 days. Some of the seasonal flu symptoms are as follows:

  • In the initial stages of flu symptoms, a person may develop a fever, with temperature of up to 104 ° Fahrenheit. This fever usually disappears after a few days.
  • The infected person also feels exhausted during the early days. He may get tired by doing the least amount of work. The tiredness also disappears after a few days.
  • These stages of flu symptoms are usually followed by a stuffy nose and a sore throat.
  • During this period, the infected person may also suffer from body ache. These aches may be so severe that the person may be confined to his bed for a number of days. These aches usually occur in the lower back and in the legs.
  • Eyes of the person may suffer from irritation. In some cases, the person may also suffer from ophthalmic infections like conjunctivitis.
  • The person may also suffer from frequent head aches.
  • Influenza may also lead to stomach disorders like abdominal pains, and diarrhea. One should note that these symptoms correspond to gastroenteritis as well and hence, should not be confused as flu, unless accompanied by other seasonal flu symptoms.
  • In case, an individual is taking drugs to fight cancer or smokes regularly, then he is likely to have more severe symptoms due to influenza. Flu is also prevalent in children below the age of 5 and in individuals above the age of 65, who already suffer from some chronic disease.
  • In serious cases, flu may also lead to pneumonia. Often, death among flu patients is caused, because of this condition.
People often confuse the seasonal flu symptoms with those of common cold. Flu symptoms are usually more severe than those of common cold and last for a longer period of time. Thus, one should not believe that one has flu, if one has fever. Statistics show that only 25 % of the people who have fever are suffering from flu.

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my hair is always falling out, i have low energy levels, low libido, major mood swings and I'm not even ovulating! Guess the next step is some medication to get me back on track! Hang in there girls!

12) i am also having same problems - depression,mood swings,loss of hair,weight gain. In my case I have developed dermoid and endometrium thickness, PCOD. Even after consulting two or three doctors and taking medicines for one year, things did not improve. Now I have switched to homeopathy and is finding some improvement. As it's just one month since I started taking medicines, I am hoping for some positive results.

11) My first pregnancy resulted in a miscarriage. The doctor monitored my levels with second pregnancy to keep from miscarrying. I also had to take the progesterone with my third pregnancy because levels were actually lower than the doctor wanted.

I now have diabetes and hypothyroidism and after reading the above info I am wondering if my progesterone has something to do with those two health issues.

I have issues that really bring me to a conclusion of PMDD. I am going to make an appointment with my doctor to see if the progesterone has anything to do with my diabetes and hypothyroidism as well as needing to find some help with the symptoms that coincide with PMDD as they are ruining my life!

10) Same case with me. i used to have so much tension and I always had bad moods. I have started taking medicines since last week but still i don't feel much change.

9) I am in the process of being testing for low hormone levels and thyroid dysfunction because, quite tragically, I've lost at least half of my hair in one month! I'm only 32 and feel like I'm having a nightmare!

I tell myself things could be much worse, but dealing with hair drastically, severely, suddenly falling out everywhere is emotionally exhausting. Has anyone else had this? What do I do?

8) I had all these symptoms of depression: panic attacks, hot flashes, insomnia, fuzzy thinking, and I was tired of seeing doctors and them not helping me with my problems.

So they recommended to me this female doctor and she tested my levels of progesterone and i was very low, so now she is treating me my progesterone. I feel a little better now. I have been treated for three months now but I know this medication is going to help me.

7) Because male doctors are often not attuned to female symptoms or concerns. The best help might come from a specialist in bioidentical hormones.

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Tuberculosis can develop after inhaling droplets sprayed into the air from a cough or sneeze from an infected person and it can also spread through infected sputum and there is a form spread through milk from infected cows. The risk of contracting TB increases with the frequency of contact with people who have the disease, and with crowded or unsanitary living conditions and poor nutrition.

Pulmonary TB develops in the minority of people whose immune systems do not successfully contain the primary infection. The disease may occur within weeks after the primary infection, or it may lie dormant for years before causing disease. The extent of the disease can vary from minimal to massive involvement, but without effective therapy, the disease becomes progressive.

Infants, the elderly, and individuals who are immunocompromised, those undergoing transplant surgery who are taking anti rejection medications are at higher risk for progression of the disease or reactivation of dormant disease. Those who have not received BCG immunisation are advised to do so and if for travel purposes, at least six weeks before departure to ensure a protective level of immunity.

Treatment with anti microbial drugs is effective but is prolonged and requires medical supervision. It is also expensive and not always available abroad. Incomplete treatment of TB infections (such as failure to take medications for the prescribed length of time) can contribute to the emergence of drug-resistant strains of bacteria.

Prevention: Avoid overcrowded places in endemic areas, particularly where spitting is common. Never drink unpasteurised milk. If in doubt, boil it before drinking. There is a vaccination (BCG) which can give a valuable degree of protection, particularly in children. Travellers who plan to spend more than a month in an area with a high tuberculosis rate and who have not been previously immunised should consider immunisation with BCG.

(Severe Acute Respiratory Syndrome)
is a severe pneumonia that has been reported in China Hong Kong, Vietnam, Singapore, Taiwan, Indonesia, the Philippines, Thailand and Canada. It appears to have spread in a short period of time and is now regarded by the World Health Organisation as a worldwide threat.

The organism responsible for SARS was originally thought to be a paramyxo virus similar to the viruses responsible for causing measles and mumps but It has now been identified as a member of the coronavirus family never previously seen in humans. Identification of the coronavirus means that scientists can now move towards developing treatments for SARS and successfully controlling the disease. At present there is no specific treatment.

Outbreaks such as the one in Toronto which affected family members and health care workers are thought to have occurred early in the epidemic when the significance of the condition was not appreciated. Where infection control measures are applied, outbreaks seem not to occur. Therefore, anyone thought to be suffering from the illness should be isolated and nursed using barrier techniques. Secondary infections can be controlled with antibiotics and symptomatic treatment undertaken.

Avian Influenza (Bird Flu)

Avian influenza usually does not make wild birds sick, but can make domesticated birds very sick and kill them. They do not usually infect humans; however, several instances of human infections and outbreaks have been reported since 1997. When such infections occur, public health authorities monitor the situation closely because of concerns about the potential for more widespread infection in the human population.

The reported symptoms of avian influenza in humans have ranged from typical influenza-like symptoms (e.g., fever, cough, sore throat and muscle aches) to eye infections, pneumonia, acute respiratory distress, viral pneumonia, and other severe and life-threatening complications.

Currently there is no definitive evidence of human-to-human transmission of avian influenza and no infections have been documented among health-care workers. While it is unusual for people to get influenza infections directly from animals, such transmission has been documented several times in recent years and is under investigation although most human cases have been linked to direct contact with diseased birds.

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Neben der medikamentösen Therapie ist insbesondere bei Kindern eine ausreichende Flüssigkeitszufuhr wichtig. Um möglichst rasch wieder gesund zu werden, kann es helfen, die Schleimhäute feucht zu halten (zum Beispiel durch Inhalationen mit heißem Wasserdampf) und sich gesund zu ernähren. Außerdem braucht der Körper in dieser Situation viel Ruhe, um sich zu erholen. Dies hilft auch, möglichen Komplikationen vorzubeugen. Auf Alkohol und Rauchen sollte gänzlich verzichtet werden.

Die verwendete Literatur finden Sie im Quellenverzeichnis.

zuletzt aktualisiert 25.10.2017
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Symptome. Oft realisiert man gar nicht, dass man eine Grippe hat: In 80 Prozent der Fälle
verläuft die Infektion mit Influenza unbemerkt oder nur wie eine leichte

Die Influenza, auch („echte“) Grippe oder Virusgrippe genannt, ist eine durch Viren aus
den Gattungen Influenzavirus A oder B ausgelöste Infektionskrankheit bei

Grippe (Influenza): Symptome, Behandlung, Verlauf -

Grippe (Influenza) kann milde Symptome auslösen, aber auch schwer verlaufen. Die nächste
Grippewelle kommt bestimmt. Was tun?

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Influenza / Anzeichen und Verlauf -

Typisch für eine Influenza ist der plötzliche Beginn der Aber auch schon einzelne
Symptome wie hohes Fieber und unproduktiver Husten können auf eine Grippe

Grippewelle 2018: Das müssen Sie jetzt zu Influenza wissen

Die kalte Jahreszeit sorgt gerade für Grippechaos. Hier erfahren Sie alles zu Symptomen
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Influenza Symptome, Ursachen sowie Behandlung, Gefahren und Verlauf. Neben ersten
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4 Symptome. Typisch ist ein plötzlicher und heftiger Ausbruch der Krankheit. Die Symptome
gleichen zum Teil denen einer starken Erkältung (die im Volksmund auch oft

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wird. Grippe ist sehr ansteckend. Besonders in den Wintermonaten erkranken

Wie steckt man sich an? Für die saisonale Influenza ist der Mensch das einzige Reservoir
und damit die einzige Infektionsquelle. Ansteckend sind vor allem Erkrankte

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The Necroa Virus begins with with four unique transmission options: Zoonotic Shift, Blood 1, Saliva 1, and Segmented Genome. All of these options run the risk of revealing a disease early, as they increase the likelihood of mutations and thus should be used only to accelerate the amount of infected players have right before they unleash zombies on the world, and their plague has been revealed.

As its name suggests, Zoonotic Shift is needed to gain access to Bird 1, Insect, Rodent 1, Bat 1, and their respective tier 2. Blood 1 is needed to gain access to Air 1, and can be connected to the Saliva 1 transmission tree by Urogenital Expansion. Both the Blood 1 and Saliva 1 transmission trees increase infectivity through the blood and bodily fluids, as well through air and water. Segmented Genome only increase the likelihood of the mutation.

  • Zoonotic Shift: Genetic shift in the virus increase infectivity, mutation chance, and makes cross species infection possible. Increases future research speed.
  • Bat 1: Host range broadens to include bats, which are hard to detect. Increases infectivity and mutation chance.
  • Bat 2: Partial genetic activation causes bats to mob and attack humans at night. Sign efficiently increases infectivity and attacks can be lethal.
  • Rodent 1: Host range broadens to include rats. Increases infectivity, especially in urban regions.
  • Rodent 2: Partial genetic activation causes rat packs to attack humans. Significantly increases infectivity, especially in urban regions.
  • Bird 1: Host range broadens to include birds. Increases infectivity, land transmission, and mutation chance.
  • Bird 2: Partial genetic activation triggers random bird attack on humans. Significantly increases infectivity and land transmission.
  • Insect: Insects susceptible to infection. Carriers increase infectivity, especially in hot climates and chance of mutation.
  • Saliva 1: Virus replicates faster in salivary glands - increasing chance of infection through contact with saliva.
  • Saliva 2: Virus replicates directly in nasal cavity - significantly increasing chances of infection through contact with mucus.
  • Gastrointestinal Expansion: Virus can replicate in stomach and intestines, increasing infectiousness through feces and vomit.
  • Water 1: Virus can survive outside the body in fresh, warm water. Increase in infectivity, especially in humid environments and ship transmission.
  • Water 2: Virus able to survive in chemically treated water. Increase infectivity, especially in humid environments and ship transmission.
  • Urogenital Expansion: Virus can replicate in kidneys and urinary tract, increasing infectiousness through urine and bodily fluids.
  • Blood 1: Virus enters the circulatory system, blood is now a transmission vector. Poor countries particularly vulnerable.
  • Blood 2: Virus can replicate directly in the blood stream, significantly increasing infectivity. Poor countries particularly vulnerable
  • Air 1: Virus bypasses alveolar macrophages in lungs to enter bloodstream. Increase infectivity, especially in arid environments and plane transmission.
  • Air 2: Virus can travel on dust particles. Increases infectivity, especially in arid environments and plane transmission.
  • Air 3: Virus replicates rapidly in aerosolised brain matter. Significantly increases risk of infection if interacting with zombie brains.
  • Segmented Genome: Virus splits its genomes into smaller molecules - increasing the likelihood of a viable mutation during transmission.

The Necroa Virus starts off with the Insomnia and Hyper Salivation trees. The disease itself gives the player two options, unlike the usual one, of wiping out humanity to complete the game: the first, and more difficult one, is infecting all of humanity and killing them through lethal symptoms (Cannibalism, Psychosis, etc.). The second and easier, but still hard one, is using the Cytopathic Reanimation symptom to produce zombies.

Using the first choice, the symptoms deal with the mental state and metabolic abilities of the infected. The second choice is unique, as it brings a whole new tree of symptoms once zombies are unleashed on the world. These symptoms, however, don't hinder or damage the zombies due to their unique condition. Instead, these symptoms actually improve the abilities of the zombies. Such symptoms include:

  • Hyper Salivation: Inflammation of the submandibular gland increases saliva production and infection rates
  • Insomnia: Inability to sleep causes irritability and tiredness. Slows future research speed
  • Fever: Increase in temperature causes general feeling of sickness and reduces concentration. Slows future research speed
  • Polyphagia: Compulsive hunger forces continuous eating. Lack of hygiene increases risk of infection.
  • Photophobia: Sensitivity and pain when eyes exposed to sunlight. Slows future research speed, but slightly reduces infection rates
  • Gastroenteritis: Inflammation of the GI tract causes frequent vomiting. Significantly increases infection rates
  • Delirium: Reduction in cognitive functions causes irritability and paranoia. Can be fatal and slows future research speed
  • Coma: Pressure build-ups in the brains stem can cause loss of consciousness. Significantly slows future research speed, but reduces infection rates
  • Cannibalism: Extreme compulsion to bite and eat other humans - significantly increases infectivity as well as lethality
  • Psychosis: Psychotic episodes lead to occasional bursts of extreme violence, which can be lethal. Increases infectivity and slows future research speed
  • Autophagia: Compulsion to bite or partially devour own body - typically fingers or own skin. Increases infection rates
  • Acute Encephalitis: Multiple inflammatory lesions in the brain causes severe neurological damage resulting in death.

  • Cytopathic Reanimation: Formation of complex neural structures enables re-animation of damaged cells and restoration of low level vitals. Turns the dead into zombies.
  • Anaerobic Resuscitation: Infected brain cells switch to anaerobic respiration. Lactic acid buildup is lethal and destroys higher brain processes and personality.
  • Enhanced Sensory Integration: Nutrient flow to occipital and temporal lobes increased causing enhanced sight and hearing. Increases severity.
  • Enhanced Motor Control: Nutrient flow to parietal lobe increased, improving movement and coordination. Increases severity, particularly in urban environments.
  • Hyperosmia: Thinning of nasal epithelium significantly increases zombie sense of smell. Increases severity.
  • Temporal Lobe Manipulation: Zombies attracted to movement and will abandon victims once dead. Prey more likely to remain and become a zombie.
  • Adrenal Surge: Mutation of the adrenal cortex causes adrenaline over-production. Increases alertness and aggression of zombies.
  • Masticatory Tension: Masticatory muscles become engorged, allowing zombie to bite through thick clothing. Severity increased.
  • Peptide Surge: Growth hormone production triggers extreme metabolism of fat to build muscle. Enhanced strength, increases severity.
  • Cathemeral Shift: Stimulation of primary visual cortex improves vision in bright sunlight. Significantly increases severity.
  • Lumbrical Hypertrophy: Significantly strengthens zombie grip making it nearly impossible for prey to break free. Severity significantly increased.
  • Anabolic Boost: Surges of testosterone significantly increases muscle mass and weight of some zombies. Severity significantly increased.
  • Acidic Reflux: Extreme laryngopharyngeal reflux causes acidic saliva. Increases severity and gives zombies combat advantage.
  • Dermal Calcification: Mutations in the endocrine system cause parts of the skin to harden and calcify. Gives zombies combat advantage.
  • Vampiric Hunger: Some zombies prefer to suck the blood from its prey rather then eat its flesh. Prey more likely to remain intact and become a zombie.
  • Naja Mortis: Muscle growth around the submandibular duct lets some zombies projectile spit at prey. Increase severity and zombie combat advantage.
  • Cranial Elephantitis: Adenoma triggers mutated growth hormones, which encourage bone growth in the skull. Gives zombies combat advantage.
  • Autothysis: Explosive mix of hydrogen sulfide and methane collects inside zombie. Significantly increases severity and zombie combat advantage.
  • Bone Dysplasia: Increased bone density provides enhanced protection against trauma. Gives zombie combat advantage.

At the start of the game, players will only have access to the basic three abilities of Heat Resistance 1, Cold Resistance 1, and Drug Resistance 1, as well as their trees.

  • Cold Resistance 1: Pathogen evolves to withstand cold temperatures and climates.
  • Cold Resistance 2: Lower intracellular water volume prevents freezing. Increased effectiveness in cold climates.
  • Heat Resistance 1: Pathogen evolves to withstand hot temperatures and climates.
  • Heat Resistance 2: Pathogen avoids cellular breakdown in high temperature. Increased effectiveness in hot climates.
  • Drug Resistance 1: Pathogen becomes resistant to class 1 and class 2 antivirals. Increase effectiveness in wealthy countries.
  • Drug Resistance 2: Pathogen develops resistance to class 3 and class 4 antivirals. Increase effectiveness in wealthy countries.
  • Genetic Hardening: Pathogen becomes harder to analyze in lab. Decrease future research speed.
  • Genetic ReShuffle 1: Pathogen DNA strands reassembled. More work needed to develop cure.
  • Genetic ReShuffle 2: A new strain of the pathogen exists, increasing work needed to develop a cure.

  • Mummification: A severely decayed zombie is able to enter a state of hibernation. Reduces rate of zombie decay.
  • Horde Instinct: Active ability lets zombies form hordes to travel across land and water to attack new lands.
  • Horde Mentality: Zombies more likely to follow others. Zombie horde size increases into the thousands.
  • Horde Vocalisation: Horde leaders attract nearby zombies with distinctive moans. Hordes can have hundreds of thousands of zombies.
  • Horde Pheromones: Horde leaders produce pheromones to attract zombies to them. Zombie hordes can be millions strong or more.
  • Structured Travel: Zombies focus on horde leaders - focusing the horde on the direction of travel and increasing travel speed.
  • Drifting Fermentation: Controlled decomposition causes zombies to bloat. Horde can drift in sea currents - significantly increasing ocean travel speed.
  • Dyskinetic Movement: Involuntary movements keep zombie coordinated with the horde - improving movement speed.
  • Echopraxia Frontal lobe damage causes infected to mimic each others' movement patterns, improving navigation of obstacles and overall speed of horde.
  • Engorged Quadriceps: Nutrients are stripped from other parts of the corpse and used to repair leg muscles to improve horde speed.
  • Autolytic Decay: Virus slows release of digestive enzymes from cells' lysosomes - slowing decomposition of corpse.
  • Putrefactive Resistance: Virus prevents anaerobic microorganisms from digesting proteins - slowing decomposition of corpse.
  • Liquefactive Resistance: Virus denatures hydrolytic enzymes, slowing liquefactive necrosis and decomposition of corpse.
  • Regenerative Activation: Active ability enables neurological regeneration in the brains of infected corpses - effectively reanimating some of the dead.
  • Ambush Predation: Reanimated zombies often remain still - waiting for humans to approach them. Reanimated zombies get combat advantage.
  • Liquefactive Necrosis: Reanimated zombies have partially liquefied internal organs, which rupture easily. Reanimated zombies get combat advantage.
  • Regenerative Bio-Synthesis: Enhanced neurological regenerative proteins allow corpses with severe head injuries to be reanimated.
  • Epidermal Digestion: Digestive enzymes break down the skin of the corpse to provide nutrients. Enables reanimation of severely mutilated corpses.
  • Cranial Metastasis: Partial neuron development triggered in the lungs - allowing some decapitated corpses to reanimate.

Like the Trojan Planes active ability in Neurax Worm, the Zombie Horde active ability is effective in infecting hard-to-reach countries, as well overwhelming countries, especially ones where Z Com is established. Its abilities both increase the horde's speed and effectiveness when crossing oceans, as well as increasing the horde's coordination and size to the point where the final abilities in its tree of this type allows hordes to number in the millions. Finally, the Reanimate active ability allows for the reanimation of deceased zombies and corpses. This ability is effective in replenishing destroyed countries by zombie populations for attacks on other healthier ones, as well as wearing out the Z Com when your initial zombie force proves to be ineffective in overwhelming them at first. Its upgrades continue to improve the combat effectiveness and abilities of the zombies reanimated.

The symptom Cytopathic Reanimation renders the cure useless in stopping a player's disease. Over the course of the game while playing this disease type, one can amass a large amount of DNA, which can be incredibly useful to those trying to obtain a victory with no zombies, or quickly decimate human populations with evolved zombies. The zombie symptoms prove to be very useful in improving their combat effectiveness and severity against humans.

Active Abilities also allow for the player to infect healthy countries with zombie hordes, as well as reanimating the dead. As with the Simian Flu and the Neurax Worm, the Necroa Virus' Active Abilities can be used to infect countries that have shut their borders.

For this plague type, transmissions increase the chance of symptom mutation. As a result, few transmissions can be purchased in order to prevent mutation that could risk early detection, which is an advantage that one should keep as long as possible due to the disease being very easy to detect in early stages and the cure developing very fast, especially when severity and lethality are high.

With this said, it is very difficult even on Casual difficulty to win with no zombies, thus unlocking the Not Another Zombie Game achievement. This is due to the player's plague having to be in a constant state of incognito for it to infect a sizable portion of the world population.

Hypothyroidism can be diagnosed by a doctor with a TSH (thyroid-stimulating hormone) test and an evaluation of your symptoms. Symptoms of hypothyroidism may be general, such as tiredness and constipation, and can often be confused with other health conditions. Symptoms usually appear slowly, over several months or years. No one can predict exactly which symptoms a person will develop or how severe the symptoms will be. Some people have many symptoms by the time they are diagnosed with hypothyroidism. Others have few, if any, symptoms. Because the symptoms are so variable, it’s important to talk with your doctor about your symptoms and to have a TSH test.

Here are some common symptoms* to look out for:

Weight gain due to fluid retention

Increased sensitivity to cold

Brittle fingernails and hair

acheter isoptine lp

Two to five years

Six to 11 years

Nasal irrigation with saline17

Six to 10 years

3 to 9 mL per nostril

Up to three weeks

Pelargonium sidoides (geranium) extract (Umcka Coldcare)18

One to 18 years

10 to 30 drops (depending on age)

Two to five years

Six to 11 years

One to 10 years

Syrup, 15 mg per 5 mL

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    This serious disease is caused by one of the smallest viruses known to man called Canine Parvovirus (CPV).(Parvo is the Latin for small). As many as 300 000 virus particles will fit into a millimeter!

    Albeit so small the virus is extremely tough and will survive most disinfectants. It may stay alive in the environment for as long as two years if conditions are favourable. In 1978 when the first cases of Parvovirus in dogs were seen, the virus spread all over the world in a matter of months, often without the involvement of dogs in the transmission.

    Massive numbers of virus occur in the stool of a sick dog. One gram of faeces may contain enough virus to infect 10 million susceptible dogs!

    The virus need certain enzymes to grow. These enzymes are found in rapid growing cells like the ones lining the intestinal tract. These cells grow quickly enough so that the intestinal lining is renewed every two to three days. If the virus grow inside these cells they break up leaving large areas of damaged lining that lead to severe loss of body fluids. The normal intestinal flora which under ordinary circumstances are pretty harmless, can now invade the body through the damaged areas.

    • Often a high fever
    • Listlessness
    • No appetite
    • Continuous vomiting or foaming at the mouth
    • Very smelly diarrhoea that frequently becomes blood-tinged
    • White or bluish gums
    • Abdominal pain
    • Dehydration � animals appear to have lost weight overnight

    The symptoms usually appear very suddenly and susceptible pups may die within a few hours. Pups with large numbers of antibodies wil show much lighter symptoms. In rare instances animals may develop infection of the heart muscles with fatal results.

    A bitch with good immunity against parvo will transfer these antibodies to her pups in the uterus. They will then be protected to a large degree for a period of six to twelve weeks. Exposure to the virus, whether naturally or through vaccination wil enhance this immunity. Healthy puppies, like the one on the left should thus be vaccinated at six weeks of age, again four weeks later and preferably a third time another four weeks later. It is very unlikely that a pup that has had three properly administered vaccinations will contract the disease. It is however important to stress that puppies must be healthy and free from worms before they can be vaccinated.

    Because Parvovirus is one of the most frustrating diseases a vet has to put up with, vaccination remains the only efficient way of saving the puppy owner a lot of tears and regret.

    At present there are no affordable injectable drugs that kill viruses in the body, thus no specific treatment exists once the virus is inside the body. Treatment is aimed at curbing secondary bacteria, stopping vomiting and replenishing body fluids.

    • Antibiotics
    • Anti-emetics
    • Intravenous fluid administration
    • Inteflora or similar probiotics to replenish gut flora (beneficial bacteria in the intestines)
    • Activated charcoal to bind toxins in the gut
    • Oral electrolytes if animals are still drinking and not vomiting
    • Small quantities of bland food eg. rice and cooked chicken
    • Blood transfusion in very severe cases

    Semen allergy suspected in rare post-orgasm illness

    LONDON (Reuters) - A mysterious syndrome in which men come down with a flu-like illness after an orgasm may be caused by an allergy to semen, Dutch scientists said on Monday.

    Men with the condition, known as post orgasmic illness syndrome or POIS and documented in medical journals since 2002, get flu-like symptoms such as feverishness, runny nose, extreme fatigue and burning eyes immediately after they ejaculate. Symptoms can last for up to week.

    Marcel Waldinger, a professor of sexual psychopharmacology at Utrecht University in the Netherlands, published two studies in the Journal of Sexual Medicine which suggest that men with POIS have an allergy to their own semen, and that a treatment known as hyposensitization therapy can help reduce its impact.

    “These results are a very important breakthrough in the research of this syndrome,” Waldinger said in a telephone interview. He said the findings “contradict the idea that the complaints have a psychological cause” and show that an auto-allergic reaction to semen is the most likely cause.

    Although it has been documented in scientific papers since 2002, post orgasmic illness syndrome is largely unknown among family doctors and experts say many men who suffer the condition feel ashamed about it and confused about what is wrong.

    Waldinger said while the syndrome is probably rare, it is likely that many men who suffer with it do not know it is a recognized condition and so do not come forward to doctors.

    For these studies, Waldinger and colleagues analyzed 45 Dutch men who were diagnosed with the illness.

    “They didn’t feel ill when they masturbated without ejaculating, but as soon as the semen came from the testes. after that they became ill, sometimes within just a few minutes,” Waldinger said.

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    Forgetfulness is often believed to be just another part of aging, but for many menopausal women, it is directly linked to their changing hormones. According to a study that was published in the journal “Menopause,” foggy memory is often most problematic during the early post-menopause years, and women may struggle with even routine mental tasks.

    Menopause brings with it many physical changes. In some cases, symptoms can be mild while in others, they can be dramatic and can cause significant disruption to your life. As many as a third of women experience mood swings during perimenopause and menopause. Emotional meltdowns, sudden tears and increased emotional instability may also have an underlying clinical origin, which is why it is important to discuss your symptoms with your health care provider.

    Tossing and turning is not the best way to get a good night’s sleep, but it becomes increasingly common as a woman approaches and goes through menopause. Decreased hormone production and the cessation of periods is a normal part of aging, but the sudden and often-tumultuous changes associated with hormonal fluctuations can cause a wide range of symptoms varying in degree from mild to severe. Many women experience trouble sleeping due to night sweats and other issues.

    Menopause brings with it numerous physical and emotional changes. Many women experience an increase in stress, anxiety levels and may even suffer from panic attacks. These may be due not to a sudden onset of psychiatric problems or emotional issues, but are instead related to the dramatic hormonal fluctuations associated with menopause. Women in perimenopause, or the period before menopause, are also likely to experience an increase in anxious feelings and stress.

    Women who tend to be sensitive to the hormonal changes that occur throughout life may also be more sensitive to the hormonal fluctuations of menopause. If you suffered from premenstrual syndrome, experienced mood swings during pregnancy or suffered from post-partum depression, you may also be more likely to suffer from depression during menopause. Women who have a personal or family history of being clinically depressed may also be at an increased risk.

    Hormonal fluctuations are a fact of life for women throughout most of their lives. Women who suffer from menstrual migraines may be more likely to also suffer from headaches during perimenopause and menopause. That is because the uneven hormone changes associated with perimenopause and menopause can trigger migraines and other types of head pain. Unfortunately, this kind of pain can interfere with your daily life and relationships and increase feelings of anxiety or irritability.

    Aches and pains are commonly accepted as normal parts of aging. However, pain all over the body can also be associated with menopause. In fact, more than half of women experiencing menopause or perimenopause, the period of time preceding menopause, will experience joint pain, discomfort and widespread pain.

    Most women begin to experience menopause symptoms in their mid- to late-40s, and while their symptoms may vary widely and range from mild to severe in intensity, most have few serious or long-term consequences. Losing bone mass, however, is one symptom that should never be taken lightly or ignored. Osteopenia and osteoporosis refer to the porous bones that become more common in older women.

    Joint pain can severely interfere with your life. The stiffness, inflammation and slow movement of painful joints can slow you down and make you feel old before your time. Although many people associated painful, swollen joints with aging or arthritis, it can often be associated with hormonal imbalances, and once these imbalances are treated, the symptoms and discomfort can be alleviated. If you are suffering from joint inflammation, addressing hormonal issues can allow you to once again enjoy a healthy, active, fully engaged life.

    Osteopenia is the precursor to osteoporosis, a condition that increases the risk of bone fractures due to a severe decrease in bone density. Women’s bone mass reaches peak density when they are in their 20s and early 30s, and as they age, their bone mass begins to decrease. After menopause, the bone loss accelerates primarily due to the loss of estrogen, which reduces collagen levels.

    Many women consider hair loss to be a man’s problem, so when they notice their brush has more hair in it and their hair feels thinner than it once did, they can experience quite a shock. Is their hair thinning? It’s quite possible. The hormonal changes, including decreased estrogen and progesterone, associated with menopause can cause noticeable thinning of the hair, and it occurs in half of women by the time they reach 50. Unlike baldness in men, however, women’s hair loss tends to be more diffuse and spread evenly throughout the scalp, which leads to overall thinning rather than a single area of baldness.

    Menopause brings with it many changes, including changes to your appearance. Thinning or sagging skin can lead to premature aging while diffuse hair loss can cause thinner hair. The same hormonal fluctuations that cause these changes can also cause thin or brittle nails. While many other symptoms of perimenopause and menopause can have a serious effect on your life, thinning hair and nails may not. However, they can have an impact on your self-esteem and leave you feeling self-conscious about the way you look.

    Recent research reveals that more than 25 percent of post-menopausal women are at risk of losing teeth. A study published in Community Dentistry and Oral Epidemiology examined more than 1,000 women who had undergone menopause, and nearly 300 of them lost a tooth during the five-year study. The tooth loss is believed to be related to hormone deficiencies and osteoporosis, but women who are overweight, smoke, have poor oral health or diabetes may be at an ever greater risk of losing teeth.

    Red, swollen and bleeding gums are generally symptoms of gingivitis or gum disease, but they can also be linked to menopause. The hormone swings of menopause and perimenopause can cause gums to become irritated and inflamed and increase the risk of gum irritation, redness, swelling, bleeding and other oral health problems.

    Hot flashes are a well-known symptom of menopause, and while burning tongue may not be as well known, it can be just as bothersome. Burning sensations in the mouth are usually linked to the hormonal fluctuations associated with menopause, and they can be easily ignored or attributed to other factors. However, burning tongue can be associated with dental health complications, including reduced saliva flow, a change in saliva composition, changes in nerve function and severe pain.

    Women who are entering menopause will often go through many different physical and emotional changes. Their bodies can change shape, and they can begin to gain weight often around their midsections. These changes are generally directly or indirectly related to the hormonal fluctuations and declines in estrogen production. Losing muscle mass is a common menopause symptom that can cause weight gain, back pain, aches and pains.

    Menopause refers to the cessation of monthly periods and the end of a woman’s fertility. Most women begin to experience menopause symptoms in their middle to late 40s and their last period in their 50s.

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    What can you do if you have PD?

    • Work with your doctor to create a plan to stay healthy. This might include the following:
      • A referral to a neurologist, a doctor who specializes in the brain
      • Care from an occupational therapist, physical therapist or speech therapist
      • Meeting with a medical social worker to talk about how Parkinson's will affect your life
    • Start a regular exercise program to delay further symptoms.
    • Talk with family and friends who can provide you with the support you need.

    For more information, visit our Treatment page.

    Watch and share this public service announcement featuring U.S. Senator Cory Booker that discusses the early warning signs of Parkinson's disease.

    Page reviewed by Dr. Chauncey Spears, Movement Disorders Fellow at the University of Florida, a Parkinson’s Foundation Center of Excellence.

    Melissa Kaplan's
    Lyme Disease
    Part of the Chronic Neuroimmune Diseases Information Resources for CFS, FM, MCS, Lyme Disease, Thyroid, and more.
    Last updated January 1, 2014

    Short Symptom List: Lyme Disease & Common Co-Infections

    Borrelia, Babesia, Bartonella, and Ehrlichia

    The following symptoms were excerpted from Diagnostic Hints And Treatment Guidelines For Lyme And Other Tick Borne Illnesses, by Joseph J. Burrascano Jr., M.D. (Fifteenth Edition 2008).

    (Borreliosis, neuroborreliosis; also known as Lyme Disease)
    Spread primarily though the bite of infected ticks that live on a wide range of mammalian species; secondary human-to-human transmission through semen, breast milk, and possibly in utero

    Bladder dysfunction
    Burning or stabbing sensations
    Cardiac impairment
    Change in bowel function
    Chest pain
    Difficulty thinking
    Difficulty with concentration and reading
    Difficulty with speech, writing
    Difficulty finding words; name blocking
    Disorientation: getting lost, going to wrong places
    Disturbed sleep: too much, too little, fractionated, early awakening
    Ears/Hearing: buzzing, ringing, ear pain, sound sensitivity
    Exaggerated symptoms or worse hangover from alcohol
    Eyes/Vision: double, blurry, increased floaters, light sensitivity
    Facial paralysis (Bell's palsy)
    Fatigue, tiredness, poor stamina
    Heart block
    Heart murmur
    Heart palpitations
    Heart valve prolapse
    Increased motion sickness
    Irritable bladder
    Joint pain or swelling
    Mood swings
    Muscle pain or cramps
    Neck creaks & cracks
    Neck stiffness, pain
    Pelvic pain
    Poor attention
    Poor balance
    Poor short-term memory
    Problem absorbing new information
    Pulse skips
    Rib soreness
    Sexual dysfunction or loss of libido
    Shooting pains
    Shortness of breath; cough
    Skin hypersensitivity
    Sore throat
    Stiffness of the joints or back
    Swollen glands
    Testicular pain
    Twitching of the face or other muscles
    Unavoidable need to sit or lay down
    Unexplained breast pain
    Unexplained fevers, sweats, chills or flushing
    Unexplained hair loss
    Unexplained menstrual irregularity'
    Unexplained milk production
    Unexplained weight loss or gain
    Upset Stomach or abdominal pain

    Babesia is a protozoan spread by ticks, blood transfusion, and in utero. Despite there being 20+known forms to date, current testing only looks for two of them.

    Air hunger
    Imbalance without true vertigo
    Mild encephalopathy
    Shaking chills

    (Bartonellosis, also known as cat scratch fever)
    Spread by bites from infected ticks and in utero

    abnormal liver enzymes
    flu-like malaise
    hemolysis with anemia
    high fever
    immune deficiency
    papular or angiomatous rash
    sore throat
    weakened immune response

    Bites from infected ticks

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    Influenza (also known as the flu) is a contagious respiratory illness caused by flu viruses. It can cause mild to severe illness, and at times can lead to death. The flu is different from a cold. The flu usually comes on suddenly. People who have the flu often feel some or all of these symptoms:

    • Fever* or feeling feverish/chills
    • Cough
    • Sore throat
    • Runny or stuffy nose
    • Muscle or body aches
    • Headaches
    • Fatigue (tiredness)
    • Some people may have vomiting and diarrhea, though this is more common in children than adults.

    Most people who get influenza will recover in several days to less than two weeks, but some people will develop complications as a result of the flu. A wide range of complications can be caused by influenza virus infection of the upper respiratory tract (nasal passages, throat) and lower respiratory tract (lungs). While anyone can get sick with flu and become severely ill, some people are more likely to experience severe flu illness. Young children, adults aged 65 years and older, pregnant women, and people with certain chronic medical conditions are among those groups of people who are at high risk of serious flu complications, possibly requiring hospitalization and sometimes resulting in death. For example, people with chronic lung disease are at higher risk of developing severe pneumonia.

    To receive weekly email updates about Seasonal Flu, enter your email address:

    Influenza, or the the flu, is a contagious respiratory illness caused by an airborne virus. Influenza viruses are divided into three types: A, B and C. Type A and B viruses are the most serious and are responsible for the flu epidemics experienced nearly every winter. Type C viruses typically cause a very minor respiratory illness and may result in no symptoms at all. The annual flu vaccine targets types A and B. While type A and B viruses differ in origin, the symptoms are the same.

    Unlike a cold, the flu usually comes on suddenly. Symptoms can be moderate to severe and typically include fever, chills, nonproductive cough, sore throat, runny or stuffy nose, muscle and body aches, headache and fatigue. Some who get the flu may also experience vomiting and diarrhea, although this is more common in children than adults. According to the Centers for Disease Control and Prevention, fever is common but does not always accompany the flu. Any fever and body aches usually last 3 to 5 days, but the cough and fatigue may last up to 2 weeks or longer. Complications can be serious and include pneumonia, bronchitis and sinus and ear infections. Young children, the elderly, pregnant women and those with compromised immune systems are at greater risk for complications.

    The flu is passed from person to person through the air. When an infected person coughs or sneezes, airborne droplets can land in the mouth or nose -- or even be inhaled into the lungs -- of others nearby. A person might also become infected by touching a surface that has the virus on it, such as a door knob, and then touching his mouth or nose. Adults are thought to be contagious 1 day before showing symptoms and 5 to 7 days after becoming sick. Children may be contagious for longer than 7 days. Symptoms usually appear within 1 to 4 days of the virus entering the body. Some people may have the flu virus and remain asymptomatic but still pass the virus to others.

    Contact your doctor if you have flu symptoms. Treatment is aimed at reducing the severity of symptoms and may include medications to relieve aches and fever, bed rest and plenty of fluids. Your doctor may also prescribe antiviral medications. When started within the first 2 days, they can reduce the duration of symptoms.

    The CDC recommends that everyone 6 months old and older get the annual flu vaccine. The vaccine is especially important for high-risk groups, including young children, pregnant women and the elderly. While the vaccine doesn’t protect against all flu viruses, it does protect against those that research indicates will be most prevalent, including type A viruses. In addition to getting the vaccine, avoid close contact with sick people. If you are sick with the flu, stay home and minimize contact with others until you are fever free for at least 24 hours. Cover your mouth and nose with a tissue when you cough or sneeze, and dispose of tissues properly. Wash your hands often with soap and water. Avoid touching your eyes, nose and mouth.

    Learn about the symptoms of flu, what to look for and what to do if you become ill.

    Some people get mildly ill, while others get very sick.

    Flu symptoms usually include the sudden appearance of: